A 15-year-old girl is being treated in hospital after being seriously injured in a shooting in Toxteth on Tuesday.
Police received reports that shots had been fired on Upper Warwick Street at around 5.10pm.
A short time later, a man, in his 20s, turned up at hospital with a gunshot injury to his hand.
Merseyside police are investigating if the two incidents are linked and are carrying out house-to-house, forensic and CCTV enquiries.
Chief Inspector Col Rooney said: “While I understand this is a shocking incident for the local community we have a large police presence in the area carrying out a number of lines of enquiry.”
An investigation is underway and a number of roads in the area have been sealed off as enquiries continue.
Mayor of Liverpool Joanne Anderson described the incident as ‘alarming and upsetting’ while Merseyside police commissioner Emily Spurrell said it was ‘deeply shocking’.
Ch Insp Rooney added: “The investigation is in the very early stages as we seek to establish what has taken place and who was involved.
“I would ask anyone who was in the area of Upper Warwick Street around 5.10pm this evening who saw or heard anything suspicious or thinks they have captured anything significant on their mobile phone, dashcam or Ring doorbell to contact us as a matter of urgency.
“There is no room for guns on the streets of Merseyside and we will do everything we can to find the person or people responsible for this incident and bring them to justice.”
How to contact police
Anyone with information is asked to DM @MerPolCC or @CrimestoppersUK on 0800 555 111 anonymously quoting log 647 of 1st March.