Liverpool and Arsenal go head-to-head for the second time in as many months at the Emirates Stadium (16.30 GMT).
But they put their Premier League title battle aside with the focus now on the FA Cup third round. The Reds and the Gunners shared an entertaining 1-1 draw at Anfield on 23 December and another close battle could be in store.
Ahead of the game, here's the latest team news for both sides.
1. Jurrien Timber - out
The summer signing from Ajax suffered a serious knee injury on his Premier League debut in August and has been sidelined since.
2. Fabio Vieira - out
A groin injury has meant the midfielder has been absent since November.
3. Thomas Partey - out
The midfielder was back in Arsenal training but Arteta admitted earlier this week that Partey has had a setback.
4. Takehiro Tomiyasu - out
The defender has been Asian Cup duty with Japan, who went out yesterday.