The Reds welcome Manchester City to Anfield (16.30 BST kick-off) with both sides aiming to put down an early marker in the title race.
Pep Guardiola’s men regained their crown last season after Liverpool won their first gong in 30 years the previous campaign.
Here’s all the key information you need to know.
What’s the team news?
Jurgen Klopp was at full strength for Tuesday night’s 5-1 demolition of Porto in the Champions League.
The Reds boss will again put out his best side ahead of the international break.
However, Liverpool will be without Trent Alexander-Arnold, who is absent with a groin injury. It’s likely that James Milner will again deputise at right-back for successive matches.
Thiago Alcantara remains sidelined with a calf injury, while Harvey Elliott is a long-term absence as he recovers from a dislocated ankle.
What about City?
The visitors will be without Ilkay Gundogan, who will be absent until after the international break.
John Stones is closing in on his return to first-team action but is unlikely to start. The centre-back is behind Aymeric Laporte and Ruben Dias in the pecking order.
Liverpool (4-3-3): Alisson, Milner, Matip, van Dijk, Robertson, Fabinho, Henderson, Jones, Salah, Jota, Mane.
Man City (4-3-3): Ederson, Walker, Laporte, Dias, Cancelo, Fernandinho, Rodri, De Bruyne, Mahrez, Sterling, Grealish.
Is the match on TV?
Yes. The game will be broadcast on Sky Sports Main Event and Sky Sports Premier League. Coverage starts at 16.00.
Can I stream the match?
Yes. Sky Sports subscribers can stream the game via Sky Go.
Can I stream the match if I don’t subscribe to Sky Sports?
Yes. You can purchase a Now TV Sports Day pass for £9.98.
How can I watch highlights?
Extended highlights will be on Match of the Day on Sunday evening, with the programme starting at 22.30.
For all the post-match analysis, follow our coverage on LiverpoolWorld.