Konate, 22, put in a brilliant outing in the San Siro as the Reds placed themselves in a 2-0 lead going into the second leg at Anfield in three weeks’ time.
The defender completed 88.9% of his passes, made four interceptions and boasted a 7.73 rating from WhoScored.com.
Jurgen Klopp’s men weren’t at their usual best in Italy and could have found themselves behind on a number of occasions, but they remained defensively solid with Konate partnering Virgil van Dijk in the centre of defence.
After the game, van Dijk was announced Man of the Match for his contributions but speaking on CBS Sports after the game, Thierry Henry and Jamie Carragher lauded Konate for his performance.
“What a game by Konate. He was absolutely outstanding tonight,” the former Arsenal striker said.
“Yes [being surprised that van Dijk was rewarded the MOTM trophy], I thought Konate was Man of the Match for me.”
Carragher, who made 737 appearances for the Reds, was also impressed by Konate’s performance and character after being up against one of the most prolific strikers in Eden Dzeko.
The 44-year-old said: “I thought Virgil van Dijk played well, but you almost expect it.
“When Konate comes in he’s not first choice exactly as it’s Matip normally, he’s a young player coming in. He’s also up against the cauldron of the atmosphere there.”
Konate has now played 15 games for Jurgen Klopp’s side since moving from RB Leipzig last summer. Whilst he has been the second choice behind the van Dijk and Matip partnership in the Premier League, the defender has started in Liverpool’s three previous Champions League fixtures.