The Goodison Park clash will be the first time the Toffees have ever come up against the Hertfordshire side and they will be looking to avoid what could be one of the biggest all time cup upsets.
There are 79 places in the English football pyramid separating the two clubs ahead of the match but the non-league side have already made it this far by claiming the scalps of other club who were far stronger on paper.
Here is everything you need to know about Everton’s FA Cup opponents ahead of Thursday’s fifth round match:
Who are Boreham Wood FC?
Established in 1948, Boreham Wood Football Club hail from the town of Borehamwood in Hertfordshire.
Their home ground of Meadow Park stadium, which has a capacity of just over 4500, is a 400 mile round trip to Goodison Park.
The club currently sit fourth in the National League table, just eight points behind league leaders Stockport County.
They have won 16 league matches so far this season, drawn eight and lost just three.
Who plays for Boreham Wood FC?
One name that Everton fans may remember is former Newcastle United striker Nile Ranger.
The 30-year old featured for the Magpies ins the 2010/11 Premier League season and has since turned out for several clubs across the Football League including Blackpool and Southend United.
Another familiar name may be that of striker Dennon Lewis, although perhaps not for footballing reasons.
The Watford youth academy graduate is best known for his appearance on the fifth series of popular ITV2 reality series Love Island.
Ex-Nottingham Forest striker Josh Rees is the clubs top scorer in the National League this season with eight.
Who is Boreham Wood FC manager?
Former AFC Wimbledon defender Luke Garrard has been in charge of Boreham Wood since October 2015.
Everton have had seven permanent bosses in the time that Garrard has been in charge of the National League side.
He has been in charge for 318 matches and has won 119 of them for an overall win percentage of 37.42%.
Garrard had two spells as a player with the club, hanging up his boots at the end of the 2015 season having re-joined from Wimbledon in 2010.
How did Boreham Wood reach the FA Cup fifth round?
Boreham Wood pulled off a major upset in the fourth round of the FA cup as the knocked out Championship title chases Borunemouth.
Captain Mark Ricketts scored the only goal in a 1-0 win at the Vitality Stadium to send his side through.
They had to knock out other EFL opponents just to set up the meeting with the Cherries, beating League One Wimbledon 2-0 in the third round.
Their second round match was against rivals St Albans, which they won 4-0 after beating Eastleigh 1-0 in the first round.
They have had to play five matches just to get to this stage.